Intensive Bio Complete Cream

A pure encapsulated retinol cream that improves the appearance of fine lines and hyperpigmentation while increasing skin firmness, with minimal risk of irritation


This variant is currently sold out.

Please fill in the form below if you'd like to be notified when it becomes available.

Free shipping on all orders & free returns. Details
  • Product details
  • What the science says
  • How to use it
  • Featured ingredients list
  • What you should know:

    This lightweight, fast-absorbing cream features 0.5% encapsulated retinol, to provide high-concentration retinol results with less risk of irritation and dryness. It renews both the skin’s surface and its lower layer to simultaneously brighten and smooth as well as clear congested pores, to reduce breakouts. The product is also formulated with dermatan sulfate analog (DSA) and chondroitin sulfate analog (CSA), to promote firmer, younger-looking skin.

    Treats these skin concerns:
    • acne
    • hyperpigmentation
    • sun damage
    • uneven texture
    Ideal for these skin types:
    • normal
    • mature
    Formulation notes:

    oil-free, fragrance-free, gluten-free, paraben-free

    Suitable for these skin tones:
    Fair Type I
    Light Type II
    Medium Type III
    Tan Type IV
    Brown Type V
    Deep Type VI

    Learn more about how we use the Fitzpatrick scale

    • Retinol is a gentler relative of tretinoin, the active ingredient in prescription-only Retin-A. It delivers similar results, with fewer side effects.
    • In a clinical study, 77% of participants saw an improvement in overall skin appearance and smoothness in two weeks. After four weeks, subjects noted improvement in fine lines, wrinkles, and hyperpigmentation.
    • Encapsulated retinol is a type of retinol that is wrapped in a protective barrier, which makes it both more stable and less likely to cause irritation, since it can penetrate more deeply into the skin.
    • P.M.:

    Apply at night to clean skin, avoiding your eye area.

    • RealSelf tips:

    • When introducing retinol into your routine, it’s best to start slowly—retinol may cause dryness, redness, and flaking. To avoid irritation, begin by using Intensive Bio Complete Cream once or twice a week. Gradually increase use to every other night, then nightly as your skin builds a tolerance. If you’re concerned about a potential skin reaction, you may want to start with Bio Complete Serum. At 0.15%, its lower retinol concentration is suitable for the most sensitive skin types.

    • To further prevent irritation, follow application with a nourishing moisturizer like Senté Ultralight Defense Moisturizer, which counteracts dryness and can help strengthen your skin barrier.

    • Retinol can increase your skin’s sensitivity to the sun, so wear a broad-spectrum sunscreen with an SPF of at least 30 daily, to protect your skin.

  • Full ingredients list:

    Water (Aqua), Caprylic/Capric Triglyceride, Ethylhexyl Olivate, Dimethicone, Glycerin, Niacinamide, Acetamidoethoxyethanol, Sodium Acrylates Copolymer, Sodium Dermatan Sulfate, Sodium Chondroitin Sulfate, Rhodosorus Marinus Extract, Palmaria Palmata Extract, Retinol, Sodium PCA, Erythritol, Carrageenan, Lecithin, Linoleic Acid, Palmitic Acid, Oleic Acid, Stearic Acid, Tocopherol, Phytosteryl Canola Glycerides, Dimethylmethoxy Chromanol, Hydroxymethoxyphenyl Decanone, Triolein, Hydroxyacetophenone, Tocopheryl Acetate, Ceramide NP, Sodium Carrageenan, Sea Salt, Xanthan Gum, Laureth-23, Propanediol, 1,2-Hexanediol, Polyglyceryl-4 Olivate, Polysorbate 20, Cetyl Palmitate, Trideceth-6 Phosphate, Sodium Hydroxide, Phenoxyethanol, Disodium EDTA, Caprylyl Glycol