Dermal Repair Ultra-Nourish

A rich, hydrating moisturizer that helps soothe and soften dry, sensitive skin while improving the appearance of fine lines and wrinkles.


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  • Product Details
  • What the science says
  • How to use it
  • Featured ingredients
  • What you should know

    This highly nourishing formula was developed with the brand’s patented heparan sulfate analog (HSA), lipids, and ceramides to enhance hydration and support the skin’s structure and cellular regeneration. The gentle cream helps soothe redness and irritation and softens rough texture, leaving behind smooth, plumper-looking skin with less visible fine lines and wrinkles. It seals in long-lasting moisture, making your skin look healthier and more radiant.

    Treats these skin concerns:
    • dehydration
    • dryness
    • inflammation
    • uneven texture
    • fine lines and wrinkles
    Ideal for these skin types:
    • normal
    • dry
    • oily
    • combination
    • sensitive
    • mature
    • acne-prone

    non-comedogenic, paraben-free, fragrance-free, gluten-free, hydroquinone-free

    Suitable for these skin tones:
    Fair Type I
    Light Type II
    Medium Type III
    Tan Type IV
    Brown Type V
    Deep Type VI

    Learn more about how we use the Fitzpatrick scale

    • Heparan sulfate is a natural sugar found in the body that’s essential for skin health. As we age, our bodies lose their natural stores of it, which leads to increased skin dehydration and inflammation.
    • Heparan sulfate analog (HSA) is a stable compound with a lower molecular weight than naturally occurring heparan sulfate, which is too large to penetrate the skin when applied topically. Senté’s patented HSA effectively delivers this active ingredient into the skin, where it works to prevent transepidermal water loss and support collagen and elastin fibers.
    • A.M./P.M.

    Massage a quarter-size amount into skin morning and night after cleansing your face and applying your serum of choice.

    • RealSelf tips:

    • Because of its rich texture, apply Senté Dermal Repair Ultra-Nourish as the last step in your skin-care routine (but before sunscreen in the morning).

    • If you have sensitive or dry skin, try “sandwiching” your retinoid or retinol product between two layers of Senté Dermal Repair Ultra-Nourish at night, to help offset some of the drying effects of vitamin A.

  • Full ingredients list:

    Ingredients: Aqua/Water/Eau, Dimethicone, Glycerin, 2,3-Butanediol, Caprylic/Capric Triglyceride, Jojoba Oil/Macadamia Seed Oil Esters, Heparan Sulfate, Acetyl Glucosamine, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, lsododecane, Brassica Campestris (Rapeseed) Seed Oil, Linoleic Acid, Lecithin, Squalene, Opuntia Ficus-lndica Flower Extract, Phytosteryl Canola Glycerides, Sodium Lauroyl Lactylate, Camelina Sativa Seed Oil, Triolein, Ceramide NP, Phytosterols, Ceramide AP, Phytosphingosine, Cholesterol, Ceramide EOP, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Oleic Acid, Palmitic Acid, Phytosteryl Macadamiate, Dimethicone/PEG-10/15 Crosspolymer, Sodium Chloride, Tocopheryl Acetate, Dimethicone/Vinyl Dimethicone Crosspolymer, Aminopropyl Dimethicone, Xanthan Gum, Carbomer, Tocopherol, Stearic Acid, Dipropylene Glycol, Sodium Citrate, Ethylhexylglycerin, Phenoxyethanol